Christiana Papamichael

Trial Manager

I completed my B.Sc in Neuroscience at the University of Manchester (2005-2008) which led me to pursue a Ph.D in Neuroscience-Chronobiology at the University of Surrey (2008-2012); after which I decide to move away from bench research and to step into clinical trials management .

In December 2013 I joined the Clinical Trials Research Centre (CTRC) at University of Liverpool as a Clinical Trials Manger. Over a period of 4 years, I was responsible for the timely and efficient day-to-day management of a multicentre international Phase IV paediatric clinical trial in epilepsy (EDIBLE) and acted as the safety reporting back-up on a number or CTIMP and non-CTIMP trials in fields including emergency care, arthritis, cancer and HIV.

I have extensive experience in all aspects of clinical trials management including but not limited to planning, set-up, monitoring, pharmacovigilance, reporting, close-down, governance (UK and overseas), compliance, budgeting, financial reporting, risk planning, documentation and development of data capture methods.

I joined the Tropical Clinical Trials Unit (tCTU) at LSTM in November 2017. My role as a Trial Manager primarily involves managing DolPHIN2 (Dolutegravir in Pregnant HIV Mothers and their Neonates). DolPHIN2 (Dolutegravir in Pregnant HIV Mothers and their Neonates) a Phase III randomised controlled clinical trial assessing the effectiveness of dolutegravir (new strategy) versus efavirenz (standard of care) based combination antiretroviral therapy, on reducing mother-to-chid-transmission in late-presenting HIV-positive mothers. The clinical trial is taking place in Uganda and South Africa and aims to provide robust safety and efficacy data for the use of Dolutegravir as a first line therapy in this vulnerable population and operational guidance for implementation across Sub-Saharan Africa.

UK Trial Managers Network, affiliate member since 09/04/2014

Institute of Clinical Research, registered member (RICR, W109414) since 15/11/2016